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Skeletal clues apparently distinguishing Waldenstrom's macroglobulinemia from multiple myeloma and leukemia

Identifieur interne : 001279 ( Main/Exploration ); précédent : 001278; suivant : 001280

Skeletal clues apparently distinguishing Waldenstrom's macroglobulinemia from multiple myeloma and leukemia

Auteurs : Bruce M. Rothschild (médecin) [États-Unis] ; F. Ruhli [Suisse] ; C. Rothschild [États-Unis]

Source :

RBID : ISTEX:E82EEFFBA9E8F2670D057117EE25864C95217F67

Abstract

This study was conducted to characterize macroscopically and by conventional radiography the bony lesions in a case of Waldenstrom's macroglobulinemia and to compare and contrast it with those of the other major hematologic lymphoproliferative disorders, multiple myeloma and leukemia. Two varieties of lytic skeletal lesions were found in Waldenstrom's macroglobulinemia. One was sharply defined, spheroid lesions with smooth borders and effaced/erased trabeculae. The second was in the form of coalescing pits (holes) with smooth, minimally remodeled edges. The appearance combined features of multiple myeloma and leukemia, but were mutually exclusive in those diseases. Spheroid lesions with effaced edges were absent in leukemia, while pits were absent in multiple myeloma. Fronts of resorption were not noted in Waldenstrom's macroglobulinemia. The combination of some of the features of leukemia and myeloma appear to allow recognition of Waldenstrom's macroglobulinemia. Am. J. Hum. Biol. 14:532–537, 2002. © 2002 Wiley‐Liss, Inc.

Url:
DOI: 10.1002/ajhb.10077


Affiliations:


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Le document en format XML

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